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What is it? Alfalfa is an herb. People use the leaves, sprouts, and seeds to make medicine. Alfalfa is used for kidney conditions, bladder and prostate conditions, and to increase urine flow. It is also used for high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, upset stomach, and a bleeding disorder called thrombocytopenic purpura. People also take alfalfa as a source of vitamins A, C, E, and K4; and minerals calcium, potassium, phosphorous, and iron. How effective is it? Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate. The effectiveness ratings for ALFALFA are as follows: Possibly effective for... * Lowering cholesterol in people with high cholesterol. Taking alfalfa seeds seems to lower total cholesterol and “bad” low-density lipoprotein (LDL) cholesterol in people with high cholesterol levels. Insufficient evidence to rate effectiveness for... * Kidney problems. * Bladder problems. * Prostate problems. * Asthma. * Arthritis. * Diabetes. * Upset stomach. * Other conditions. More evidence is needed to rate alfalfa for these uses. How does it work? Alfalfa seems to prevent cholesterol absorption in the gut. Are there safety concerns? Alfalfa leaves are POSSIBLY SAFE for most adults. But taking alfalfa seeds long-term is LIKELY UNSAFE. Alfalfa seed products may cause reactions that are similar to the autoimmune disease called lupus erythematosus. Alfalfa might also cause some people's skin to become extra sensitive to the sun. Wear sunblock outside, especially if you are light-skinned. Special precautions & warnings: Pregnancy or breast-feeding: Using alfalfa in larger than food amounts is POSSIBLY UNSAFE during pregnancy and breast-feeding. There is some evidence that alfalfa may act like estrogen, and this might affect the pregnancy. “Auto-immune diseases” such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Alfalfa might cause the immune system to become more active, and this could increase the symptoms of auto-immune diseases. There are two case reports of SLE patients experiencing disease flare after taking alfalfa seed products long-term. If you have an auto-immune condition, it’s best to avoid using alfalfa until more is known. Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Alfalfa might have the same effects as the female hormone estrogen. If you have any condition that might be made worse by exposure to estrogen, don’t use alfalfa. Diabetes: Alfalfa might lower blood sugar levels. If you have diabetes and take alfalfa, monitor your blood sugar levels closely. Kidney transplant: There is one report of a kidney transplant rejection following the three-month use of a supplement that contained alfalfa and black cohosh. This outcome is more likely due to alfalfa than black cohosh. There is some evidence that alfalfa can boost the immune system and this might make the anti-rejection drug cyclosporine less effective. Are there interactions with medications? Major Do not take this combination. Warfarin (Coumadin) Alfalfa contains large amounts of vitamin K. Vitamin K is used by the body to help blood clot. Warfarin (Coumadin) is used to slow blood clotting. By helping the blood clot, alfalfa might decrease the effectiveness of warfarin (Coumadin). Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed. Moderate Be cautious with this combination. Birth control pills (Contraceptive drugs) Some birth control pills contain estrogen. Alfalfa might have some of the same effects as estrogen. But alfalfa isn't as strong as the estrogen in birth control pills. Taking alfalfa along with birth control pills might decrease the effectiveness of birth control pills. If you take birth control pills along with alfalfa, use an additional form of birth control such as a condom. Some birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1/35, Ortho-Novum 7/7/7), and others. Estrogens Large amounts of alfalfa might have some of the same effects as estrogen. But even large amount of alfalfa aren't as strong as estrogen pills. Taking alfalfa along with estrogen pills might decrease the effects of estrogen pills. Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others. Medications that decrease the immune system (Immunosuppressants) Alfalfa might increase the immune system. By increasing the immune system, alfalfa might decrease the effectiveness of medications that decrease the immune system. Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others. Medications that increase sensitivity to sunlight (Photosensitizing drugs) Some medications can increase sensitivity to sunlight. Large doses of alfalfa might also increase your sensitivity to sunlight. Taking alfalfa along with medication that increase sensitivity to sunlight could make you even more sensitive to sunlight, increasing the chances of sunburn, blistering or rashes on areas of skin exposed to sunlight. Be sure to wear sunblock and protective clothing when spending time in the sun. Some drugs that cause photosensitivity include amitriptyline (Elavil), Ciprofloxacin (Cipro), norfloxacin (Noroxin), lomefloxacin (Maxaquin), ofloxacin (Floxin), levofloxacin (Levaquin), sparfloxacin (Zagam), gatifloxacin (Tequin), moxifloxacin (Avelox), trimethoprim/sulfamethoxazole (Septra), tetracycline, methoxsalen (8-methoxypsoralen, 8-MOP, Oxsoralen), and Trioxsalen (Trisoralen). Are there interactions with herbs and supplements? Vitamin E Alfalfa might interfere with the way the body takes in and uses vitamin E. Are there interactions with foods? There are no known interactions with foods. What dose is used? BY MOUTH: * For high cholesterol: a typical dose is 5-10 grams of the herb, or as a steeped strained tea, three times a day. 5-10 mL of a liquid extract (1:1 in 25% alcohol) three times a day has also been used. Other names Feuille De Luzerne, Lucerne, Luzerne, Medicago, Phyoestrogen, Purple Medick, Medicago Sativa. The following doses have been studied in scientific research: Alfalfa (play /ælˈfælfə/; Medicago sativa) is a flowering plant in the pea family Fabaceae cultivated as an important forage crop in the US, Canada, Argentina, France, Australia, the Middle East, South Africa, and many other countries. It is also known as lucerne in the UK, France, Australia, South Africa and New Zealand, and known as lucerne grass in south Asia. It superficially resembles clover, with clusters of small purple flowers. Contents * 1 Ecology * 2 Culture * 3 Harvesting * 4 Worldwide production * 5 Alfalfa and bees * 6 Varieties o 6.1 Genetically modified alfalfa + 6.1.1 Legal issues * 7 History * 8 Phytoestrogens in alfalfa * 9 Medical uses * 10 Gallery * 11 References * 12 External links [edit] Ecology Alfalfa is a perennial forage legume which normally lives 4-8 years, but can live more than twenty years, depending on variety and climate.[2] The plant grows to a height of up to 1 metre (3 ft), and has a deep root system, sometimes stretching more than 15 metres (49 ft).[2] This makes it very resilient, especially to droughts.[2] It has a tetraploid genome.[3] Alfalfa is a small seeded crop, and has a slowly-growing seedling, but after several months of establishment, forms a tough 'crown' at the top of the root system. This crown contains many shoot buds that enables alfalfa to re-grow many times after being grazed or harvested. This plant exhibits autotoxicity, which means it is difficult for alfalfa seed to grow in existing stands of alfalfa.[4] Therefore, it is recommended that alfalfa fields be rotated with other species (for example, corn or wheat) before reseeding.[5] [edit] Culture Alfalfa is widely grown throughout the world as forage for cattle, and is most often harvested as hay, but can also be made into silage, grazed, or fed as greenchop.[6] Alfalfa has the highest feeding value of all common hay crops, being used less frequently as pasture.[5] When grown on soils where it is well-adapted, alfalfa is the highest yielding forage plant.[7] Its primary use is as feed for dairy cattle—because of its high protein content and highly digestible fiber—and secondarily for beef cattle, horses, sheep, and goats.[8][9] Humans also eat alfalfa sprouts in salads and sandwiches.[10][11] Dehydrated alfalfa leaf is commercially available as a dietary supplement in several forms, such as tablets, powders and tea.[12] Alfalfa is believed by some to be a galactagogue, a substance that induces lactation.[13] Like other legumes, its root nodules contain bacteria, Sinorhizobium meliloti, with the ability to fix nitrogen, producing a high-protein feed regardless of available nitrogen in the soil.[14] Its nitrogen-fixing abilities (which increases soil nitrogen) and its use as an animal feed greatly improved agricultural efficiency.[15][16] Alfalfa can be sown in spring or fall, and does best on well-drained soils with a neutral pH of 6.8 – 7.5.[17][18] Alfalfa requires sustained levels of potassium and phosphorus to grow well.[19] It is moderately sensitive to salt levels in both the soil and in irrigation water, although it continues to be grown in the arid southwestern United States, where salinity is an emerging issue.[20][21][22] Soils low in fertility should be fertilized with manure or a chemical fertilizer, but correction of pH is particularly important.[23] Usually a seeding rate of 13 – 20 kg/hectare (12 – 25 lb/acre) is recommended, with differences based upon region, soil type, and seeding method.[24] A nurse crop is sometimes used, particularly for spring plantings, to reduce weed problems and soil erosion, but can lead to competition for light, water and nutrients.[25] In most climates, alfalfa is cut three to four times a year, but it can be harvested up to 12 times per year in Arizona and southern California.[26][27] Total yields are typically around 8 tonnes per hectare (4 short tons per acre) in temperate environments, but yields have been recorded up to 20 t/ha (16 short tons per acre).[27] Yields vary with region, weather, and the crop's stage of maturity when cut. Later cuttings improve yield, but with reduced nutritional content.[28] Alfalfa leafcutter bee, Megachile rotundata, a pollinator on alfalfa flower Alfalfa is considered an insectary due to the large number of insects it attracts.[29] Some pests, such as alfalfa weevil, aphids, armyworms, and the potato leafhopper, can reduce alfalfa yields dramatically, particularly with the second cutting when weather is warmest.[30] Chemical controls are sometimes used to prevent this.[30] Alfalfa is also susceptible to root rots, including Phytophthora, Rhizoctonia, and Texas root rot.[31][32][33] Main article: List of alfalfa diseases [edit] Harvesting Cylindrical bales of alfalfa When alfalfa is to be used as hay, it is usually cut and baled.[34] Loose haystacks are still used in some areas, but bales are easier for use in transportation, storage and feed.[35] Ideally, the first cutting should be taken at the bud stage, and the subsequent cuttings just as the field is beginning to flower, or one tenth bloom for the reason that carbohydrates are at their highest.[36] When using farm equipment rather than hand-harvesting, a swather cuts the alfalfa and arranges it in windrows.[37] In areas where the alfalfa does not immediately dry out on its own, a machine known as a mower-conditioner is used to cut the hay.[34] The mower-conditioner has a set of rollers or flails that crimp and break the stems as they pass through the mower, making the alfalfa dry faster.[38] After the alfalfa has dried, a tractor pulling a baler collects the hay into bales. There are several types of bales commonly used for alfalfa. For small animals and individual horses, the alfalfa is baled into small two-string bales, commonly named by the strands of string used to wrap it. Other bale sizes are three-string, and so on up to half-ton (six-string) "square" bales — actually rectangular, and typically about 40 x 45 x 100 cm (14 in x 18 in x 38 in).[3] Small square bales weigh from 25 – 30 kg (50 – 70 pounds) depending on moisture, and can be easily hand separated into "flakes". Cattle ranches use large round bales, typically 1.4 to 1.8 m (4 to 6 feet) in diameter and weighing from 500 to 1,000 kg, (1000 to 2000 lbs). These bales can be placed in stable stacks or in large feeders for herds of horses, or unrolled on the ground for large herds of cattle.[3] The bales can be loaded and stacked with a tractor using a spike, known as a bale spear, that pierces the center of the bale,[39] or they can be handled with a grapple (claw) on the tractor's front-end loader. A more recent innovation is large "square" bales, roughly the same proportions as the small squares, but much larger. The bale size was set so stacks would fit perfectly on a large flatbed truck. These are more common in the western United States. When used as feed for dairy cattle, alfalfa is often made into haylage by a process known as ensiling.[8] Rather than drying it to make dry hay, the alfalfa is chopped finely and fermented in silos, trenches, or bags, anywhere the oxygen supply can be limited to promote fermentation.[40] The anaerobic fermentation of alfalfa allows it to retain high nutrient levels similar to those of fresh forage, and is also more palatable to dairy cattle than dry hay.[41] In many cases, alfalfa silage is inoculated with different strains of microorganisms to improve the fermentation quality and aerobic stability of the silage.[42] [edit] Worldwide production Worldwide alfalfa production Alfalfa is the most cultivated forage legume in the world.[citation needed] Worldwide production was around 436 million tons in 2006.[43][page needed] The US is the largest alfalfa producer in the world, but considerable production is found in Canada, Argentina (primarily grazed), Australia, South Africa, and the Middle East.[citation needed]. Within the United States, the leading alfalfa growing states are California, South Dakota, and Wisconsin. The upper Midwestern states account for about 50% of US production, the Northeastern states 10%, the Western states 40%, and the Southeastern states almost none.Template:USDA-NASS) Alfalfa has a wide range of adaptation, and can be grown from very cold northern plains to high mountain valleys, from rich temperate agricultural regions to Mediterranean climates and searing hot deserts.[citation needed] [edit] Alfalfa and bees Alfalfa seed production requires the presence of pollinators when the fields of alfalfa are in bloom.[3] Alfalfa pollination is somewhat problematic, however, because Western honey bees, the most commonly used pollinator, are not suitable for this purpose; the pollen-carrying keel of the alfalfa flower trips and strikes pollinating bees on the head, which helps transfer the pollen to the foraging bee.[3] Western honey bees, however, do not like being struck in the head repeatedly and learn to defeat this action by drawing nectar from the side of the flower. The bees thus collect the nectar, but carry no pollen and so do not pollinate the next flower they visit.[44] Because older, experienced bees do not pollinate alfalfa well, most pollination is accomplished by young bees that have not yet learned the trick of robbing the flower without tripping the head-knocking keel. When western honey bees are used to pollinate alfalfa, the beekeeper stocks the field at a very high rate to maximize the number of young bees.[44] Western honey bee colonies may suffer protein stress when working alfalfa only, due to shortage of one of the amino-acids comprising the pollen protein, iso-leucine. Today, the alfalfa leafcutter bee is increasingly used to circumvent these problems.[45] As a solitary but gregarious bee species, it does not build colonies or store honey, but is a very efficient pollinator of alfalfa flowers.[45] Nesting is in individual tunnels in wooden or plastic material, supplied by the alfalfa seed growers.[44] The leafcutter bees are used in the Pacific Northwest, while western honeybees dominate in California alfalfa seed production.[44] A smaller amount of alfalfa produced for seed is pollinated by the alkali bee, mostly in the northwestern United States. It is cultured in special beds near the fields. These bees also have their own problems. They are not portable like honey bees, and when fields are planted in new areas, the bees take several seasons to build up.[44] Honey bees are still trucked to many of the fields at bloom time. [edit] Varieties Small square bales of alfalfa Considerable research and development has been done with this important plant. Older cultivars such as 'Vernal' have been the standard for years, but many better public and private varieties better adapted to particular climates are available.[46] Private companies release many new varieties each year in the US.[47] Most varieties go dormant in the fall, with reduced growth in response to low temperatures and shorter days.[47] 'Nondormant' varieties that grow through the winter are planted in long-seasoned environments such as Mexico, Arizona, and Southern California, whereas 'dormant' varieties are planted in the Upper Midwest, Canada, and the Northeast.[47] 'Nondormant' varieties can be higher yielding, but they are susceptible to winter-kill in cold climates and have poorer persistence.[47] Most alfalfa cultivars contain genetic material from sickle medick (M. falcata), a wild variety of alfalfa that naturally hybridizes with M. sativa to produce sand lucerne (M. sativa ssp. varia). This species may bear either the purple flowers of alfalfa or the yellow of sickle medick, and is so called for its ready growth in sandy soil.[48] Watering an alfalfa field Most of the improvements in alfalfa over the last decades have consisted of better disease resistance on poorly drained soils in wet years, better ability to overwinter in cold climates, and the production of more leaves. Multileaf alfalfa varieties have more than three leaflets per leaf, giving them greater nutritional content by weight because there is more leafy matter for the same amount of stem[citation needed]. The California Alfalfa Workgroup [3] (UC Davis) has an up-to-date listing of alfalfa variety trial data [4] by location as well as Agronomy Progress Reports for each year. [edit] Genetically modified alfalfa Roundup Ready alfalfa, a genetically modified variety was released by Forage Genetics Int'l in 2005. This was developed through the insertion of a gene owned by Monsanto Company that confers resistance to glyphosate, a broad-spectrum herbicide, also known as Roundup. Although most grassy and broadleaf plants, including ordinary alfalfa, are killed by Roundup, growers can spray fields of Roundup Ready alfalfa with the glyphosate herbicide and kill the weeds without harming the alfalfa crop. [edit] Legal issues with Roundup Ready Alfalfa in the US Roundup Ready alfalfa was sold in the United States from 2005–2007 with more than 300,000 acres (120,000 ha) planted out of 21,000,000 acres (8,500,000 ha). After a hiatus of nearly 4 years of legal and regulatory troubles, planting resumed in February 2011. In 2006, the Center for Food Safety and Geertson Seed Farm sued USDA-APHIS to stop farmers from growing Roundup Ready Alfalfa. Their primary claim was 1) the possibility of increased spread of glyphosate-resistant weeds, and 2) the possibility that gene flow from Roundup Ready alfalfa would harm organic or conventional growers. In early 2007, The 9th Circuit Court in San Francisco decided in favor of the plaintiffs, forcing USDA-APHIS to conduct an Environmental Impact Study--this study took four years and was completed in December 2010. In May 2007, the California Northern District Court also issued an injunction order prohibiting farmers from planting Roundup Ready alfalfa until the US Department of Agriculture (USDA) completed its EIS study. As a result, the USDA put a hold on any further planting of Roundup Ready alfalfa from 2007-2011. Monsanto subsequently sued Geertson Seed, a case that went to the US Supreme Court in 2010, and decided in favor of Monsanto. (Monsanto Co. v. Geertson Seed Farms[49]).[50]In June 2010, the US Supreme Court issued a ruling on this matter, and determined that the 9th Circuit should not have prohibited further plantings, but should have allowed USDA-APHIS to determine the safety of the technology. Both sides claimed victory.[51] The final Environmental Impact Statement was issued by APHIS December, 2010, and, after a comment period, the crop was completely deregulated in January, 2011, and planting resumed in February, 2011. APHIS issued its lengthy EIS document, and considered the gene flow issue, impacts on organic growers, the issue of Roundup-resistant weeds and host of other questions, and in the end determined that Roundup-ready did not present a risk to the environment (APHIS). [edit] History A book on agriculture by the Roman writer Palladius, dated 4th century AD, includes a section about alfalfa. Palladius says: "One sow-down lasts ten years. The crop may be cut four or six times a year.... An [Roman] acre of it is abundantly sufficient for three horses all the year.... It may be given to cattle, but new provender is at first to be administered very sparingly, because it bloats up the cattle."[52] Palladius called alfalfa "medica", a name that referred to the Medes, a people who lived in ancient Iran. The ancient Greeks and Romans believed, very probably correctly, that the alfalfa plant came from the Medes land (in today's Iran). (The ancient Greeks and Romans also used the name medica to mean a citron fruit, once again because it was believed to have come from the Medes land). The ancient Roman name medica is the root of the modern scientific name for the alfalfa genus, Medicago. Despite the report in Palladius and in some other Roman and ancient Greek writers, there is little evidence that alfalfa was in widespread use in the Mediterranean region in those days. The 13th century Arabic dictionary Lisan al-Arab says that "al-fiṣfiṣa" (alfalfa) is cultivated as an animal feed and consumed in both fresh and dried form.[53] The Arabic name is believed to have come from an Iranian language. (The Persian name for alfalfa is on record in medieval times as "aspast" | "ispist"). In medieval Spain, the Arabic name "al-fisfisa" mutated into the Spanish name "alfalfa".[54] Alfalfa in medieval Spain was cultivated as fodder for horses and had a reputation as the best fodder for them. In the 16th century, Spanish colonizers introduced alfalfa to the Americas as fodder for their horses.[55] The English name "alfalfa" dates from mid-19th century far-west USA, from the Spanish. Alfalfa seeds were imported to California from Chile in the 1850s. That was the beginning of a rapid and extensive introduction of the crop over the western US States.[56] In the North American colonies of the eastern US back in the 18th century it was called "lucerne" and lots of trials at growing it were made, but generally without getting satisfactory results. Relatively very little alfalfa is grown in the eastern US still today. Today in France and Germany, and also in Britain and Australia, alfalfa is usually called "lucerne" | "luzerne", a word that arose in French in the 16th century. Since North and South America now produce a large part of the world's output, the word "alfalfa" has been slowly entering into other languages besides English and Spanish. http://www.alfalfaseed.ucdavis.edu/ http://www.tvalfalfaseed.org/ http://www.agr.mt.gov/dept/alfseedCom.asp http://www.wasga.org/ http://en.wikipedia.org/wiki/Alfalfa |