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Heart Failure
  1. What is it? Answer

  2. What causes it? Answer

  3. What are the risk factors? Answer

  4. What's normal? Answer

  5. How is it diagnosed? Answer

  6. What are the symptoms? Answer

  7. What are the signs? Answer

  8. What are the clinical findings? Answer

  9. What are the lab or investigation findings? Answer

  10. What are the workable treatment options? Answer

  11. When is counseling required? Answer

  12. When is medication required? Answer

  13. How long should medication last? Answer

  14. What type of medication is available? Answer

  15. How could this be prevented? Answer

  16. Heart failure: What can the various complications be?Answer

  17. How does this interfere with your daily routine?Answer

  18. What have statistics revealed?Answer

  19. What has recent research revealed?Answer

  20. What must you try before relying on medication?Answer

  21. What is the first line of medication?Answer

  22. What are the types? What are the types of heart failure? Answer

  23. What are the complications of this medication?Answer

  24. How can the complications of this medication be prevented?Answer

  25. Human Circulatory SystemAnswer

  26. Recanalization of chronically occluded coronary arteries Answer

Heart Failure
Congestive Heart Failure (CHF)
What is heart failure?
Less blood is pumped out of the heart to organs and tissues in the body.

Heart failure does not mean that your heart has stopped working. Heart failure can be ongoing (chronic), or it may start suddenly (acute). Basically, the heart can’t keep up with its workload. Congestive heart failure (also called heart failure) is a serious condition in which the heart doesn’t pump blood as efficiently as it should.

What will happen if heart failure is left untreated?
Premature death

What is another word or term for heart failure?
Congestive heart failure

What can cause congestive heart failure?
1. Coronary artery disease (disease of the arteries that supply blood to the heart)
2. High blood pressure
3. Cardiomyopathy (disease of the heart muscle)
4. Valvular heart diseases (diseases of the valves present in the heart)
5. Past heart attack (myocardial infarction)
6. Birth defects of the heart
7. Diabetes
8. Diseases of the covering of the heart
9. Arrhythmia (irregular heartbeat)
10. Severe infections
11. Anemia
12. Thyroid disease
13. Vitamin deficiencies
14. Drugs, such as hydroxychloroquine
15. Chronic diseases of the lungs (e.g., COPD)
16. Obesity
17. Smoking
18. Kidney diseases
19. Alcohol use

Heart failure: What are the most common causes?
1. Coronary artery disease/ischemic heart disease
2. Hypertension
3. Cardiomyopathy (disease of the heart muscle)/dilated cardiomyopathy
4. Valvular heart disease
5. Past heart attack (myocardial infarction)

What are the types of heart failure?
Heart failure can be ongoing (chronic), or it may start suddenly (acute).
The most common type of heart failure is left-sided heart failure.
1. Left-sided heart failure: This is most common type of heart failure.
2. Diastolic heart failure: Your left ventricle has become stiffer than normal. See further details of EF.
3. Systolic heart failure: The ventricle cannot contract the way it should. See further details of EF.
4. Right-sided heart failure: Right-sided heart failure is less common than left-sided heart failure.
5. Biventricular heart failure: Biventricular heart failure affects both sides of the heart.
6. Congestive heart failure: Congestive heart failure is a condition that results from heart failure on the right side, left side, or both sides of the heart.
7. Chronic heart failure: When heart failure develops over the course of multiple months or years, it is called chronic heart failure. Most cases of heart failure are chronic.
8. Acute heart failure: When heart failure develops suddenly, it is called acute heart failure. This type of heart failure is less common than chronic heart failure.
9. Decompensated heart failure: If a person has heart failure that suddenly worsens, it is known as decompensated heart failure.

What are various case scenarios?

Case 1 1991 Srinagar.

Here are the summarized case details. A 70-year-old male complains of severe chest pain. On examination, the patient is breathless, restless, sweating, and unable to stand. His systolic blood pressure is less than 90 mm Hg. The patient is transferred to the hospital emergency room. His ECG shows ST elevation and blood biochemistry indicates high cardiac enzymes, which proves myocardial infarction.

What was the diagnosis?
Acute myocardial infarction
Left-sided heart failure
Systolic heart failure
Acute heart failure

After treatment, the person recovered completely and lived for another 15 years, as circulated by Dr. Asif Qureshi.

Case 2 September 23, 2021

Valvular heart disease case.
Chronic heart failure


Ejection fraction

What is a normal ejection fraction?
A normal ejection fraction ranges from 50% to 70%.
The ventricle is filled with 100ml of blood
60 ml is ejected.
This means the ejection fraction is 60%.

What is ejection fraction?
How is EF measured?

EF can be measured in your doctor’s office during tests such as:
    * Ultrasound of the heart (echocardiography) – used most often
    * Cardiac catheterization
    * Magnetic resonance imaging (MRI) scan of the heart
    * Nuclear medicine scan (multiple gated acquisition or MUGA) of the heart; also called a nuclear stress test
    * Computerized tomography (CT) scan of the heart

What happens to the ejection fraction in diastolic and systolic heart failure?
Ejection fraction is utilized to differentiate between systolic and diastolic dysfunction.

What are the causes of diastolic dysfunction?
Hypertrophic cardiomyopathy
Restrictive cardiomyopathy
Hypertension

Is heart failure reversible?
Fix the underlying cause.
Make sure there is an appropriate treatment plan.
Stage D heart failure is not reversible.

Right-sided heart failure can be caused by left-sided heart failure.
Systolic heart failure. Failure of contraction.
Diastolic heart failure. Failure of relaxation.

Treatment can include the treatment of acute heart failure and treatment of chronic heart failure.
See also heart failure due to acute myocardial infarction.
Acute hospitalization will be required.
IV medications
Oxygenation
Sometimes ventilatory support may be required.
In case of further complications, further treatment is required.
Chronic heart failure will require oral medication.

CHF usually requires a treatment program of
* rest
* proper diet
* modified daily activities
* drugs such as
o diuretics
o ACE (angiotensin-converting enzyme) inhibitors
o beta blockers
o digitalis
o vasodilators

How do you do on a quiz relevant to this issue?

What must a specific physician do if this medical condition does not respond to the treatment?

Go ahead with stages of congestive heart failure.

What is the stage of this heart failure?
In Stage D heart failure, treatment does not help.

Stages of Congestive Heart Failure

American Heart Association endorses these stages of congestive heart failure.

What are the stages of congestive heart failure?
Stages of congestive heart failure - Stage A
Stages of congestive heart failure - Stage B
Stages of congestive heart failure - Stage C
Stages of congestive heart failure - Stage D (End-Stage)

Stages of Congestive Heart Failure - Stage A

Stage A can be a reversible diagnosis.
Here is the treatment for this situation.
1. Lifestyle changes to slow or stop disease progression.
The usual treatment plan for Stage A can include:
Engaging in regular, daily exercise
Quitting smoking
Treating high blood pressure with medications, a low-sodium diet, and an active lifestyle
Lowering cholesterol levels
Not drinking alcohol or using recreational drugs

If reducing salt intake and making lifestyle changes do not control high blood pressure, start with Hydrochlorothiazide (oral route) 12.5 mg. Take one tablet by mouth one time daily.

Stages of Congestive Heart Failure - Stage B
Usually accompanied by a reduced ejection fraction (EF).
Here is the treatment for this situation.
1. Lifestyle changes to slow or stop disease progression. See stage A guidelines.
2. Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers, if you aren’t taking any as part of your Stage A treatment plan.
3. Beta blockers if you’ve had a heart attack and your EF is 40% or lower, if you aren’t taking any as part of your Stage A treatment plan.
4. Possible surgery or intervention as a treatment for coronary artery blockage, heart attack, valve disease, or congenital heart disease.

Stages of Congestive Heart Failure - Stage C

Congestive Heart Failure - Stage C: What are the symptoms and signs?
1. Fluid retention resulting in edema (swelling) in the legs, ankles, feet, and/or abdomen.
2. Shortness of breath
3. The above are symptoms that a doctor should look for. There may be some general symptoms as well, like fatigue, decreased exercise tolerance, and increased nighttime urination.

What are the Stage C treatments of congestive heart failure?
1. Same as the Stage A or Stage B treatments.
2. Additional medications, as needed (blood pressure, heart efficiency, heart rate control, etc.).
3. If there is fluid retention, a diuretic (water pill).
4. Sodium and fluid restrictions.
5. Daily weights.

Stages of Congestive Heart Failure - Stage D (End-Stage)

The patient has symptoms even at rest and is unable to carry out any physical activity without discomfort.

With Stage D heart failure, treatment does not help.
Treatment will not make this mildly better or even a little bit better.
Symptoms do not go away.
Shortness of breath and edema do not go away.

This is also known as end-stage heart failure.

Stage D treatment options

1. Continuous intravenous medication that helps the heart pump stronger (inotropic therapy). This is an option, but impossible in the real world every day. Have a public discussion on this issue.
2. Left ventricular assistive device (LVAD). This is an option, but impossible in the real world.
3. Evaluation for a heart transplant. This is an option but impossible in the real world.
4. Palliative or hospice care. Also known as end-of-life care. Possible.

How many Americans and people worldwide had heart failure?
On or before July 22, 2021, at least 6 million Americans had heart failure.
Worldwide statistics are pending.

Heart failure: How can this be prevented? How could this be prevented?
One way to prevent heart failure is to prevent and control conditions that can cause it, such as coronary artery disease, high blood pressure, and obesity.
Not smoking
Controlling certain conditions, such as high blood pressure and diabetes
Fix underlying causes of heart failure before it progresses to Stage D
Staying physically active
Eating healthy foods
Maintaining a healthy weight
Staying away from harms


What other resources have some guidelines that are less useful, although I felt like displaying these entities?
Mayo Clinic
American Heart Association
Government health department websites

On or before July 1, 2022, your entities had not displayed the resources required in a question-and-answer format via the internet. You can display the resources required in a question-and-answer format authored by Dr. Asif Qureshi through your website.

Reimbursement for Dr. Asif Qureshi for these resources is required.

Umer Sharif
What needs to be accomplished in this case on or after 1 PM local time on September 23, 2021?
Monitor the pulse oximeter 24 hours a day, 7 days a week.
There should be 95% or above oxygen saturation by pulse oximeter.
The local specific physicians in Karachi, Sindh, need to be reminded about their responsibilities.
There is a specific case presentation a physician must make that has not be presented in this case. This shows a lack of training. The facts displayed here are from Umer Sharif’s family members and video coverage. Thanks to those who provided video coverage in the interest of his recovery. Continue further video coverage until he fully recovers.

How should local specific physicians have presented?
The 66-year-old Umer Sharif is conscious and oriented to time, space, and person. On September 22, 2021, Umer Sharif was not in a coma. Umer Sharif was able to spontaneously open his eyes, talk, and move his limbs while sitting, as evidenced in the video. Umer Sharif started having symptoms of breathlessness that were of a cardiac origin. When did these symptoms start? Where did they start? How did they start? These questions need further answers.

Latest pulse oximetry readings: Not available
Blood biochemistry: Not available
Echocardiography ejection fraction: Not available

What is ejection fraction relevant to the human heart?
Ejection fraction is a measurement of the percentage of blood pumped out of a filled ventricle each time it contracts. Ejection fraction is usually measured only in the left ventricle.

What equipment is used to measure the ejection fraction of human heart?
1. Echocardiogram
2. Cardiac catheterization
3. Magnetic resonance imaging (MRI)
4. Computerized tomography (CT)
5. Nuclear medicine scan

What is the normal ejection fraction of a human heart?
A normal ejection fraction is about 50% to 75% according to the American Heart Association.
A borderline ejection fraction can range between 41% and 50%.

What are the causes of a reduced ejection fraction of the human heart?
1. Weakness of the heart muscle, such as cardiomyopathy.
2. Heart attack (myocardial infarction) that damaged the heart muscle.
3. Heart valve problems.
4. Long-term, uncontrolled high blood pressure.

What was the ejection fraction of Umer Sharif at 1 PM on September 23, 2021?
Where is the lesion?
How did you verify the location of lesion with reasons, for example an echocardiography presentation?
Who did or will do further echocardiography?
What is the diagnosis?
What are the workable treatment options?
Who has the answer?
Who is willing to answer?
Who has the responsibility to answer?

Antihypertensive medications: What are various examples?
Antihypertensive medications: What are various examples?
Diuretics (water pills) hydrochlorothiazide
ACE inhibitors
Beta blockers
Potassium binders

What is the maximum oral dose of hydrochlorothiazide per day?
The dose is usually not more than 50 mg per day.

What are examples of diuretics?
Aldactone (spironolactone)
Bumex (bumetanide)
Demadex (torsemide)
Esidrix (hydrochlorothiazide)
Lasix (furosemide)
Zaroxolyn (metolazone)

What is the first choice of medicine for hypertension in adults in this situation?
Hydrochlorothiazide (oral route) 12.5 mg. Take one tablet by mouth one time daily.

Last Updated: July 11, 2022